It appears Jacobs Entertainment has decided to demolish the Courtyard Inn at 601 West 4th Street, rather than remodel it into the proposed 'Loft 601' project.
DEMOLITION. DEMOLISH BUILDING, SLABS, FOOTINGS, PARKING LOT. HAUL DEBRIS TO LANDFILL
Previous plans according to this now expired permit, were to renovate it in the same manner Renova Flats was renovated.
You can see in the gallery below a list of several permits previously tied to this property.